Chin Annsha Veimern, Ellyana Sungkar, Hartati Purbo Dharmadji, Laniyati Hamijoyo – Mucocutaneous Manifestation of Systemic Lupus Erythematosus Patients At Rheumatology Outpatient Clinic In Dr. Hasan Sadikin General Hospital
Background: Systemic Lupus Erythematosus (SLE) is an autoimmune systemic disease which symptoms induced by Ultraviolet rays exposure. It commonly affects women and causes wide range of symptoms. One of the organs affected is mucocutaneous. Our study aims to determine mucocutaneous manifestations of SLEpatients in rheumatology Outpatient Clinic in Dr.Hasan Sadikin General Hospital, Bandung.
Methods: A descriptive study with prospective crosssectional design conducted. Data were obtained by interviewing SLE patients as primary data and accessingmedical record as secondary data. Ninety-six SLE patients met the inclusion and exclusion criteria were included.Results: From ninety-six subjects, 94.8% subjects are working indoors. Mucocutaneous manifestation were found in most patients. Based on American College ofRheumatology (ACR) criteria, we found mucocutaneous manifestations, such as: oral ulcers in 67 patients (69.8%); malar rash in 63 patients (65.6%); photosensitivity
rash in 51 patients (53.1%), and discoid rash erythematous in 21 patients (21.9%). Specific LE cutanoeus manifestation based on Gilliam classificationwere found in our study subjects, such as papulosquamous/psoriasisform (19.5%) , morbilliform (17.7%),vesicobullous annular SCLE (13.5%), annular SCLE(6.3%), and TEN-like LE (1%). Non-specific LE cutaneous manifestations based on Gilliam classification were also found in our study subjects, such as oral ulcers (69.8%),photosensitivity rash (53.1%), alopecia (86.5%), Raynaud’s Phenomenon (39.6%), nail abnormalities (24.0%),periungual telangiectasia patients (13.5%), vasculiticlesions (12.5%), thrombophlebitis (44.8%), bullous lesion (5.2%) and erythema multiforme (5.2%).Conclusion: Mucocutaneous manifestations in SLE patients based on ACR criteria found most in this study is oral ulcers. Based on Gilliam classification specific LEcutanoeus manifestation was not found in all SLE patients,while non-specific LE mucocutaneous manifestations mostly found is alopecia.
Keywords: American College of Rheumatology (ACR)criteria, Gilliam classification, Mucocutaneous manifestations,Systemic Lupus Erythematosus