IJR Vol 2 No. 2 January 2010; Profile of osteophyte location in different grades of functional status in patients with knee osteoarthritis

O Mesanti, B Setiyohadi, YI Kasjmir, U Budihusodo, M Oemardi – Profile of osteophyte location in different grades of functional status in patients with knee osteoarthritis.

Background. Osteophyte is a reparative response to cartilage breakdown in osteoarthritis (OA) and osteophyte formation is a knee stabilizing factor. Disability could be found in patients with knee OA. Objective. To identify the profi le of osteophyte formation (location, size, and direction) based on knee radiograph and functional status examination in knee OA patients who presented to the Rheumatology Clinic, Cipto Mangunkusumo Central National General Hospital. Methods. Samples were taken by consecutive approach. Knee radiographs (weight bearing anteroposterior and 30 degrees fl exion skyline views) and functional status examinations were performed on 100 patients with knee OA (90 females and 10 males with ages ranging from 51 to 74 years old). A radiologist assessed fi lms for osteophyte profi le such as location, size, and direction according to standard atlas. One knee with the severe radiological assessment based on OA grade was selected from one patient to be the profi le. Lequesne Algofunctional Index was also taken from the patients. Results. The site of osteophyte in patients with knee OA was mostly found at lateral femur (85/100 subjects). Based on specifi c location, grade 2 osteophyte at lateral femur was the most frequent size (49/100 subjects) and osteophyte extending toward the lower middle at lateral patella (65/100 subjects) was the most frequent direction of osteophyte. The most frequent profi le for size and direction of osteophyte at specifi c location was the grade 2 osteophyte extending toward the lower middle at lateral patella (35/100 subjects). Severe functional status impairment was found in 53% of the patients. The most frequent functional status found according to specifi c location of osteophyte was severe functional status impairment in patients with osteophyte at lateral femur (46/100 subjects). The most frequent functional status of OA patients based on the size and direction of osteophyte at specifi c location was the severe functional impairment in the patients with grade 2 osteophyte at lateral femur (27/100 subjects) and the patients with osteophyte extending towards the lower middle at lateral patella (37/100 subjects) respectively. Conclusions. Osteophyte at lateral femur, osteophyte at lateral tibiofemoral compartment, grade 2 osteophyte at lateral femur, and osteophyte extending toward the lower middle at lateral patella were the profi les of osteophyte which mostly showed severe functional status impairment in patients with knee OA.